Posts in: CH250

CO2 Dance

In case you missed the CO2 dance last week, here it is!

Safety First!

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All geared up for lab!

Chromatography and the NMR

Students started week two of organic chemistry with their first major test.  They didn’t get much rest time after though, as they jumped right back into lab the next day.  This week students will be leaning how to use NMR spectroscopy as another tool for identifying organic compounds.  NMR (nuclear magnetic resonance) treats the nucleus of different atoms as tiny magnets and subjects them to an oscillating external magnetic force. The nuclei will resonate differently depending on how the are bonded to their neighbors and what their neighbors are.  If you’ve ever had an MRI at the doctors, you’ve experienced a type of NMR.   Students will be given an unknown compound and asked to identify it using the NMR and IR.

Students will also learn about different types of chromatography this week. Chromatography is a general term referring to lab techniques that are used to separate compounds from one another. They first will use column chromatography to separate ferrocene and acetyl ferrocene.

ferrocene                                                ferricebe

 

Both molecules contain iron and two five member rings, but acetyl ferrocene also contains an additional functional group. This functional group will allow acetyl ferrocene to move through a silica gel column at a different speed than the ferrocene. The originally dark orange solution of a combination of the two compounds will come out in two bands, a yellow one and a light orange one.

Students will then use thin-layer chromatography (TLC) to compare the separation on their own compounds against pure standards.  With TLC, students dot small drops of their sample on silica coated plastic. The plastic is then placed in a small amount of liquid and the liquid will carry the dots up the plate at different rates depending on the structure of the compound.

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On this sample TLC plate, the mixed sample is spotted in the the middle and a pure samples lay on either side.

 

 

 

Week One

Welcome to Chemistry 250: Structures of Organic Molecules!

We have hit the ground running full speed ahead in Orgo 1. Already students have dived into the first three (yes 3 !) chapters of their text books.  They are learning how to draw organic molecules and identify different functional groups. Functional groups are characteristic groups of bonded atoms that have predictable properties.  For example, alcohols are one type of functional group. They consist of an oxygen atom and a hydrogen atom bonded together at the end of a chain of carbons atoms.  Wood alcohol (methanol), alcohol for consumption (ethanol), rubbing alcohol (iso-propyl alcohol) and even cholesterol all have this C—O-H bond.

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The students will begin their lab work tomorrow by extracting caffeine molecules from tea leaves. During this lab they will learn basic organic techniques such as separation, filtration, recrystallization and melting point determination. This week students will also be utilizing infrared spectroscopy. IR spectroscopy is a useful tool for identifying functional groups on organic molecules.  Molecules are subjected to wavelengths of infrared light and different types of bonds will absorb the light and be excited in different ways.

If you want to learn all of the ways bonds exhibit vibrational excitation come stop by the lab at 1 on Wednesday for our awesome IR dance!